Xiaohui Li

PhD Candidate in Plant Cell Biology, Purdue University

About


[The website is still under construction. There might be some information missing.]
I am Xiaohui Li, a PhD candidate at the Department of Botany and Plant Pathology, advised by Dr. Chunhua Zhang and Dr. Chris Staiger. I am using a combination of high spatial temporal resolution live-cell imaging, chemical genetics and computational biology approaches to study plant cell dynamics.
💡

Skills

Wet lab:
  • Imaging: Confocal microscopy (Zeiss LSM 710, LSM 880), Total Internal Reflection Fluorescence (TIRF) microscopy, epifluorescence microscopy.
  • Genetics: Arabidopsis forward mutant screening and mapping
  • Biochemistry: Protein expression and purification with FPLC system, Western-blotting, protein-small molecule binding assays (MST, CETSA, DSF, DARTS).
Dry lab:
  • Computational biology: Whole genome sequencing (WGS), SNP calling and mapping, RNA-seq and ChIP-seq analysis, proteomics data analysis, multimer protein complex modeling, protein-ligand docking
  • Programming languages: UNIX/BASH, Python, R.

Education

2017-present, PhD student, Department of Botany and Plant Pathology, Purdue University, West Lafayette, IN, USA
2013-2017, B.S. of Biological Sciences, Taishan Honors College, Shandong University, Jinan, China
2015, exchange student, College of Life Science, National Tsing Hua University, Hsinchu

Publications


The catalytic domain of cellulose synthase (CESA) is involved in vesicle trafficking and protein dynamics


Lei Huang, Weiwei Zhang, Xiaohui Li, Christopher J Staiger, Chunhua Zhang

bioRxiv, 2022


Using Differential Scanning Fluorimetry (DSF) to Detect Ligand Binding with Purified Protein


Xiaohui Li, Chunhua Zhang

Plant Chemical Genomics, Methods in Molecular Biology, vol. 2213, Springer, 2021, pp. 183--186


Endosidin20 targets the cellulose synthase catalytic domain to inhibit cellulose biosynthesis


Lei Huang, Xiaohui Li, Weiwei Zhang, Nolan Ung, Nana Liu, Xianglin Yin, Yong Li, Robert E Mcewan, Brian Dilkes, Mingji Dai, Glenn R Hicks, Natasha V Raikhel, Christopher J Staiger, Chunhua Zhang

The Plant Cell, vol. 32(7), 2020, pp. 2141--2157


Endosidin2-14 targets the exocyst complex in plants and fungal pathogens to inhibit exocytosis


Lei Huang, Xiaohui Li, Yang Li, Xianglin Yin, Yong Li, Bin Wu, Huaping Mo, Chao-Jan Liao, Tesfaye Mengiste, Wei Guo, Mingji Dai, Chunhua Zhang

Plant Physiology, vol. 180(3), 2019, pp. 1756--1770


Progress in using chemical biology as a tool to uncover novel regulators of plant endomembrane trafficking


Lei Huang, Xiaohui Li, Chunhua Zhang

Current Opinion in Plant Biology, vol. 52, 2019, pp. 106--113


Interaction between VPS35 and RABG3f is necessary as a checkpoint to control fusion of late compartments with the vacuole


Cecilia Rodriguez-Furlan, David Domozych, Weixing Qian, Per-Anders Enquist, Xiaohui Li, Chunhua Zhang, Rolf Schenk, Holly Saulsbery Winbigler, William Jackson, Natasha V Raikhel, Glenn R Hicks

Proceedings of the National Academy of Sciences, vol. 116(42), 2019, pp. 21291--21301


Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor


Yanchen Tian, Min Fan, Zhaoxia Qin, Hongjun Lv, Minmin Wang, Zhe Zhang, Wenying Zhou, Na Zhao, Xiaohui Li, Chao Han, Zhaojun Ding, Wenfei Wang, Zhi-Yong Wang, Ming-Yi Bai

Nature Communications, vol. 9(1), 2018, pp. 1--13

Posts


Sep 15, 2022

Paper summary: TOR complex regulates actin cytoskeleton dynamics through controlling ATP levels | PNAS

Reference: Dai, L., Wang, B., Wang, T., Meyer, E. H., Kettel, V., Hoffmann, N., ... & Zhang, Y. (2022). The TOR complex controls ATP levels to regulate actin cytoskeleton dynamics in Arabidopsis. Proceedings of the National Academy of Sciences, 119(38)...


Read more

Contact


Xiaohui Li

PhD Candidate in Plant Cell Biology


li2902[AT]purdue.edu


Department of Botany and Plant Pathology

Purdue University, West Lafayette, IN, USA

915 W State St, West Lafayette, IN, 47907, USA


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